The field of partial reprogramming is transitioning from successful mouse studies to its first human clinical trials. At the heart of this experiment lies the discovery of Yamanaka ...

St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the ...

Dr. Lun Yu explains how advanced molecular design can enable peptides to target the biological roots of skin ageing, turning longevity science into actionable innovation ...

Systemic candidiasis is an opportunistic fungal infection that has been difficult to treat effectively. Research published in ...

Advances in iPSC technology and in vivo reprogramming are expanding the possibilities for cell therapy. Explore the science ...

The capacity of an organism to regenerate depends on cell dedifferentiation followed by proliferation. Mammals, in general, have limited regenerative capacity. Now, a team of researchers at the Salk ...

For all they do for us, our hearts aren't very good at repairing themselves. So when a person suffers a heart attack, their blood pump is left with a large amount of scar tissue, which can impede the ...

A new way of reprogramming our immune cells to shrink or kill off cancer cells has been shown to work in the otherwise hard to treat and devastating skin cancer, melanoma. The discovery demonstrates a ...

Most tissues in the body can regenerate themselves after an injury, but unfortunately heart muscle cells aren’t one of them. Now, scientists at the Max Planck Institute have shown in mice that ...

One promising strategy to remuscularize the injured heart is the direct cardiac reprogramming of heart fibroblast cells into cardiomyocytes. Researchers have identified TBX20 as the key missing ...